Sather was born in Seattle, Washington. He was nominated for an Emmy Award for his work on The Larry Sanders Show. Sather wrote for Saturday Night Live during the 1994-1995 season. His last credit was a television remake of Mr. Ed for which he was also an executive producer.

Sather died of a gunshot wound to the head on March 3, 2004. His death was ruled a suicide. He had four children with his second wife.